XRCC3 Antikörper (C-Term)
Kurzübersicht für XRCC3 Antikörper (C-Term) (ABIN786380)
Target
Alle XRCC3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Sequenz
- LADRLREEEA ALGCPARTLR VLSAPHLPPS SCSYTISAEG VRGTPGTQSH
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Homologie
- Dog: 92%, Human: 100%, Rabbit: 83%
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Produktmerkmale
- This is a rabbit polyclonal antibody against XRCC3. It was validated on Western Blot.
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Aufreinigung
- Affinity Purified
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 346 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- XRCC3 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 3 (XRCC3))
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Andere Bezeichnung
- XRCC3
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Hintergrund
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This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene functionally complements Chinese hamster irs1SF, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents and is chromosomally unstable. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.
Alias Symbols: CMM6
Protein Interaction Partner: SWSAP1, ZSWIM7, UBC, FANCG, BRCA2, ZNHIT3, RAD51D, RAD51C, RAD51,
Protein Size: 346 -
Molekulargewicht
- 38 kDa
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Gen-ID
- 7517
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NCBI Accession
- NM_005432, NP_005423
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UniProt
- O43542
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Pathways
- DNA Reparatur
Target
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