RAD23B Antikörper (Middle Region)

Produktnummer ABIN785816

Der Kaninchen Polyklonal anti-RAD23B Antikörper wird verwendet zum Nachweis von RAD23B in Proben von Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen und Zebrafisch (Danio rerio). Er wurde validiert für WB und IHC.

Kurzübersicht für RAD23B Antikörper (Middle Region) (ABIN785816)

Target: RAD23B (RAD23 Homolog B (RAD23B))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RAD23B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-RAD23B Antikörper

Bindungsspezifität: Middle Region

Sequenz: QSSAVAAAAA TTTATTTTTS SGGHPLEFLR NQPQFQQMRQ IIQQNPSLLP

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against RAD23B. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human RAD23B

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 409 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu RAD23B

Target: RAD23B (RAD23 Homolog B (RAD23B))

Andere Bezeichnung: RAD23B

Hintergrund: The protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in the nucleotide excision repair (NER). This protein was found to be a component of the protein complex that specifically complements the NER defect of xeroderma pigmentosum group C (XP-c) cell extracts in vitro. This protein was also shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, and thus this protein may be involved in the ubiquitin mediated proteolytic pathway in cells.
Alias Symbols: HHR23B, HR23B, P58
Protein Interaction Partner: PNMA5, NGLY1, PUF60, XPC, UBC, PSMD14, SHFM1, PDE12, NPLOC4, UBA6, PDLIM5, DRAP1, PLIN3, NUBP2, UBA2, EIF4A3, XPNPEP1, PKM, NUCB1, GTF2I, CBS, ADSL, PARK2, Rpl18, Rpl10a, Rac2, LOC100044627, Gm4705, Vmn2r101, Rpl34-ps1, Rpl5, Eno1b, Xpnpep3, Hist1h2bg, Hi
Protein Size: 409

Molekulargewicht: 43 kDa

Gen-ID: 5887

NCBI Accession: NM_002874, NP_002865

UniProt: P54727

Pathways: DNA Reparatur