UBE2C Antikörper (Middle Region)

Produktnummer ABIN785224

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch UBE2C in WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für UBE2C Antikörper (Middle Region) (ABIN785224)

Target: UBE2C (Ubiquitin-Conjugating Enzyme E2C (UBE2C))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UBE2C Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-UBE2C Antikörper

Bindungsspezifität: Middle Region

Sequenz: GTAVGSIRTS STVCLLSGPR ETQDSSKPLV WGLGWDMRLL LELTLQLFLQ

Homologie: Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against UBE2C. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human UBE2C

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 161 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu UBE2C

Target: UBE2C (Ubiquitin-Conjugating Enzyme E2C (UBE2C))

Andere Bezeichnung: UBE2C

Hintergrund: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE2C is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for the destruction of mitotic cyclins and for cell cycle progression.
Alias Symbols: UBCH10, dJ447F3.2
Protein Interaction Partner: ANAPC11, FZR1, KLHL2, UBE2C, PCGF3, UBC, MAPK7, UBA1, BAG3, TNNC1, CXCR1, Rag1, TTC9C, UNK, ZFYVE19, UBQLN4, UBXN1, UBQLN1, UBXN7, TTLL12, SEC24A, AHCYL1, SSSCA1, YAP1, UBE4B, USP34, ZRANB2, ATP6V1F, USP9X, UBE2V1, UBE2B, TYMS, TRIP6, PSMC6, PSMA5, PPM1G,
Protein Size: 161

Molekulargewicht: 17 kDa

Gen-ID: 11065

NCBI Accession: NM_181799, NP_861515

UniProt: O00762

Pathways: Ubiquitin Proteasome Pathway