KCNA5 Antikörper (N-Term)

Produktnummer ABIN784789

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch KCNA5 in WB. Es zeigt Reaktivität gegenüber Proben von Human, Ratte und Maus.

Kurzübersicht für KCNA5 Antikörper (N-Term) (ABIN784789)

Target: KCNA5 (Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 5 (KCNA5))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KCNA5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-KCNA5 Antikörper

Bindungsspezifität: N-Term

Sequenz: DPGVRPLPPL PEELPRPRRP PPEDEEEEGD PGLGTVEDQA LGTASLHHQR

Homologie: Human: 100%, Mouse: 93%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against KCNA5. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human KCNA5

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 613 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu KCNA5

Target: KCNA5 (Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 5 (KCNA5))

Andere Bezeichnung: KCNA5

Hintergrund: Potassium channels represent the most complex class of voltage-gated ino channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). KCNA5 encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class, the function of which could restore the resting membrane potential of beta cells after depolarization and thereby contribute to the regulation of insulin secretion.
Alias Symbols: ATFB7, HCK1, HK2, HPCN1, KV1.5, MGC117058, MGC117059, PCN1
Protein Interaction Partner: SIRT1, KCNAB2, ERBB2IP, SNTA1, HSP90AA1, TNK2, Rab11a, DCTN2, GNB2L1, KCNAB1, TFRC, SRC, PRKCQ, PRKCB, KCNA5, KCNA4, KCNA3, KCNA2, FYN, FHL1, DYNC1I1, CAV1, ACTN2, UBE2I, SUMO3, RAB5A, RAB4A, DLG4, DLG1, PTPRE,
Protein Size: 613

Molekulargewicht: 67 kDa

Gen-ID: 3741

NCBI Accession: NM_002234, NP_002225

UniProt: P22460