NR4A1 Antikörper (C-Term)

Produktnummer ABIN784750

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch NR4A1 in WB. Es zeigt Reaktivität gegenüber Proben von Human, Ratte, Maus, Hund, Rind (Kuh), Pferd, Kaninchen, Meerschweinchen und Zebrafisch (Danio rerio).

Kurzübersicht für NR4A1 Antikörper (C-Term) (ABIN784750)

Target: NR4A1 (Nuclear Receptor Subfamily 4, Group A, Member 1 (NR4A1))

Reaktivität: Human, Ratte, Maus, Hund, Rind (Kuh), Pferd, Kaninchen, Meerschweinchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NR4A1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-NR4A1 Antikörper

Bindungsspezifität: C-Term

Sequenz: RGRLPSKPKQ PPDASPANLL TSLVRAHLDS GPSTAKLDYS KFQELVLPHF

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against NR4A1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human NR4A1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 598 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu NR4A1

Target: NR4A1 (Nuclear Receptor Subfamily 4, Group A, Member 1 (NR4A1))

Andere Bezeichnung: NR4A1

Hintergrund: NR4A1 encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. Expression is induced by phytohemagglutinin in human lymphocytes and by serum stimulation of arrested fibroblasts. The encoded protein acts as a nuclear transcription factor. Translocation of the protein from the nucleus to mitochondria induces apoptosis.
Alias Symbols: GFRP1, HMR, MGC9485, N10, NAK-1, NGFIB, NP10, NUR77, TR3
Protein Interaction Partner: KRTAP10-5, KRTAP10-1, LONRF1, PGBD1, BCL2L10, CDKN2D, BCL2A1, BCL2, TUBB4A, VASP, ANKIB1, CUTA, NFKB1, SMAD3, LSS, HADHA, GLUD1, GK, CPT1A, SERPING1, ABCC6, ABCC13, SOCS4, ABCG8, DIABLO, HCVgp1, ABCA5, CHEK2, SUGT1, PRDX4, PRDX6, CHD1L, ABCB11, ARHGEF5, U
Protein Size: 598

Molekulargewicht: 64 kDa

Gen-ID: 3164

NCBI Accession: NM_002135, NP_002126

UniProt: P22736

Pathways: Fc-epsilon Rezeptor Signalübertragung, Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Steroid Hormone Mediated Signaling Pathway