SLC9A3R1 Antikörper (AA 281-358) (Cy5)

Produktnummer ABIN759300

Der Cy5-konjugierte Kaninchen Polyklonal anti-SLC9A3R1 Antikörper (ABIN759300) detektiert spezifisch SLC9A3R1 in WB, IF (cc) und IF (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für SLC9A3R1 Antikörper (AA 281-358) (Cy5) (ABIN759300)

Target: SLC9A3R1 (Solute Carrier Family 9, Subfamily A (NHE3, Cation Proton Antiporter 3), Member 3 Regulator 1 (SLC9A3R1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SLC9A3R1 Antikörper ist konjugiert mit Cy5

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-SLC9A3R1 Antikörper (Cy5)

Bindungsspezifität: AA 281-358

Homologie: Human,Mouse,Rat,Cow,Pig,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human EBP50/SLC9A3R1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu SLC9A3R1

Target: SLC9A3R1 (Solute Carrier Family 9, Subfamily A (NHE3, Cation Proton Antiporter 3), Member 3 Regulator 1 (SLC9A3R1))

Andere Bezeichnung: EBP50

Hintergrund:

Synonyms: EBP 50, EBP50, Ezrin radixin moesin binding phosphoprotein 50, Ezrin-radixin-moesin-binding phosphoprotein 50, Na+/H+ exchange regulatory cofactor NHE RF, Na+/H+ exchange regulatory cofactor NHE-RF1, Na+/H+ exchange regulatory co factor, NHERF 1, NHERF, NHERF-1, NHERF1, NHRF1_HUMAN, NPHLOP2, Regulatory cofactor of Na+/H+ exchanger, SLC9A3R1, Sodium hydrogen exchanger regulatory factor 1, Sodium-hydrogen exchanger regulatory factor 1, Sodium/hydrogen exchanger regulatory factor 1, Solute carrier family 9 sodium/hydrogen exchanger member 3 regulator 1, Solute carrier family 9 sodium/hydrogen exchanger, isoform 3 regulatory factor 1, Solute carrier family 9 isoform 3 regulatory factor 1, Solute carrier family 9 isoform A3 regulatory factor 1, Solute carrier family 9 member 3 regulator 1.

Background: Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. Necessary for recycling of internalized ADRB2. Was first known to play a role in the regulation of the activity and subcellular location of SLC9A3. Necessary for cAMP-mediated phosphorylation and inhibition of SLC9A3. May enhance Wnt signaling. May participate in HTR4 targeting to microvilli (By similarity). Interacts with MCC.

Gen-ID: 9368

Pathways: Proton Transport, Platelet-derived growth Factor Receptor Signaling, Negative Regulation of Transporter Activity, SARS-CoV-2 Protein Interaktom