CACNA1A Antikörper (AA 1401-1500)

Produktnummer ABIN751303

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch CACNA1A in ELISA, IF (cc), IF (p), IHC (fro) und IHC (p). Es zeigt Reaktivität gegenüber Proben von Ratte.

Kurzübersicht für CACNA1A Antikörper (AA 1401-1500) (ABIN751303)

Target: CACNA1A (Calcium Channel, Voltage-Dependent, P/Q Type, alpha 1A Subunit (CACNA1A))

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CACNA1A Antikörper ist unkonjugiert

Applikation: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-CACNA1A Antikörper

Bindungsspezifität: AA 1401-1500

Kreuzreaktivität: Ratte

Homologie: Human,Mouse,Cow,Pig,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CACNA1A

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu CACNA1A

Target: CACNA1A (Calcium Channel, Voltage-Dependent, P/Q Type, alpha 1A Subunit (CACNA1A))

Andere Bezeichnung: CACNA1A/Cav2.1

Hintergrund:

Synonyms: APCA, BI, Brain calcium channel 1, Brain calcium channel I, Cach4, Cacn3, Cacna1a, Cacnl1a4, Calcium channel alpha 1A subunit, Calcium channel L type alpha 1 polypeptide, Calcium channel L type alpha-1 polypeptide isoform 4, Calcium channel voltage dependent, P/Q type alpha 1A subunit, CAV2.1, EA2, FHM, HPCA, MHP, MHP1, RAT brain class A, RBA-I, SCA6, Voltage-dependent P/Q-type calcium channel alpha-1A subunit, Voltage-gated calcium channel alpha subunit Cav2.1, CAC1A_HUMAN.

Background: Cav2.1 is a voltage-sensitive calcium channels (VSCC) which belongs to the calcium channel alpha-1 subunit family. Cav2.1 mediates the entry of calcium ions into excitable cells and is also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. Cav2.1 (isoform alpha-1A) gives rise to P and/or Q-type calcium currents. Voltage-dependent calcium channels are multisubunit complexes, consisting of alpha-1, alpha-2, beta and delta subunits in a 1:1:1:1 ratio. The channel activity is directed by the pore-forming and voltage-sensitive alpha-1 subunit. In many cases, this subunit is sufficient to generate voltage-sensitive calcium channel activity. The auxiliary subunits beta and alpha-2/delta linked by a disulfide bridge regulate the channel activity.

Gen-ID: 773

Pathways: Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process