NR4A1 Antikörper (pSer351)

Produktnummer ABIN744458

Der Kaninchen Polyklonal anti-NR4A1 Antikörper wird verwendet zum Nachweis von NR4A1 in Proben von Maus. Er wurde validiert für ELISA, IHC (p), IF (cc), IF (p) und IHC (fro).

Kurzübersicht für NR4A1 Antikörper (pSer351) (ABIN744458)

Target: NR4A1 (Nuclear Receptor Subfamily 4, Group A, Member 1 (NR4A1))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NR4A1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-NR4A1 Antikörper

Bindungsspezifität: pSer351

Kreuzreaktivität: Maus

Homologie: Human,Rat,Dog,Cow,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human Nur77 around the phosphorylation site of Ser351

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu NR4A1

Target: NR4A1 (Nuclear Receptor Subfamily 4, Group A, Member 1 (NR4A1))

Andere Bezeichnung: Nur77

Hintergrund:

Synonyms: NR4A1phospho S351, GFRP 1, GFRP, GFRP1, Growth factor inducible nuclear protein N10, Growth Factor Inducible Nuclear Protein NP10, Growth Factor Response Protein 1, Hbr1, HMR, Hormone Receptor, MGC9485, N10, N10 nuclear protein, NAK 1, NAK1, NGFIB, NP 10, NP10, NR4A1, Nuclear hormone receptor NUR/77, Nuclear Hormone Receptor TR3, Nuclear Receptor Subfamily 4 Group A Member 1, NUR77, Orphan nuclear receptor HMR, Orphan nuclear receptor NR4A1, ST 59, ST59, Steroid receptor TR3, TR 3, TR3, TR3 orphan receptor, Early response protein NAK1.

Background: NUR77 is a member of the steroid/thyroid hormone receptor superfamily. The gene for NUR77 is induced rapidly by androgens/growth factors and may have functions related to cell proliferation, differentiation and apoptosis. It has been demonstrated that mouse NUR77 is necessary for induced apoptosis in T-cell hybridomas and can also be induced during early mitogenesis. NUR77 is a phosphoprotein and its size ranges from 67 kDa to 88 kDa, depending on post-translational modifications.

Gen-ID: 3164

Pathways: Fc-epsilon Rezeptor Signalübertragung, Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Steroid Hormone Mediated Signaling Pathway