AP2B1 Antikörper (AA 351-450)

Produktnummer ABIN731138

Der Kaninchen Polyklonal anti-AP2B1 Antikörper wird verwendet zum Nachweis von AP2B1 in Proben von Human. Er wurde validiert für ELISA, IF (cc), IF (p), IHC (p) und IHC (fro).

Kurzübersicht für AP2B1 Antikörper (AA 351-450) (ABIN731138)

Target: AP2B1 (Adaptor-Related Protein Complex 2, beta 1 Subunit (AP2B1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AP2B1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-AP2B1 Antikörper

Bindungsspezifität: AA 351-450

Homologie: Human,Mouse,Rat,Dog,Cow,Pig,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human beta Adaptin

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu AP2B1

Target: AP2B1 (Adaptor-Related Protein Complex 2, beta 1 Subunit (AP2B1))

Andere Bezeichnung: beta Adaptin/AP2 beta

Hintergrund:

Synonyms: Adaptin beta 1 beta prime, _-Adaptin, Adaptin _1, Adaptin-_1, Adaptin beta 2 beta, Adaptin beta 2, Adaptin, beta 2 beta, Adaptor protein complex AP 1 beta 1 subunit, Adaptor related protein complex 1 beta 1 subunit, Adaptor related protein complex 1, beta 1 subunit, Adaptor related protein complex 2 beta 1 subunit, Adaptor related protein complex 2, beta 1 subunit, ADTB 1, ADTB 2, ADTB1, ADTB2, AP 1 complex subunit beta 1, AP 105A, AP 105B, AP 2 complex subunit beta 1, AP1 Beta, AP1 complex subunit beta 1, AP105A, AP105B, AP1B1, AP2 beta, AP2 complex subunit beta 1, AP2B1, AP2beta, BAM 22, BAM22, Beta adaptin, Beta prime adaptin, Beta1 adaptin, Beta2 adaptin, CLAPB 1, CLAPB 2, CLAPB1, CLAPB2, Clathrin assembly protein complex 1, Clathrin assembly protein complex 1 beta large chain, Clathrin assembly protein complex 2 beta large chain, Clathrin associated/assembly/adaptor protein large beta 1, Clathrin associated/assembly/adaptor protein large beta 2, DKFZp781K0743, Golgi adaptor HA1/AP1 adaptin beta subunit, Plasma membrane adaptor HA2/AP2 adaptin beta subunit, Plasma membrane adaptor HA2/AP2 adaptor beta subunit, Plasma membrane adaptor HA2/AP2.

Background: Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limbs and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP2 beta appears to be required for normal face and limb development and for proper terminal differentiation and function of renal tubular epithelia.

Gen-ID: 2971

Pathways: EGFR Signaling Pathway, Neurotrophin Signalübertragung, EGFR Downregulation