UACA (UACA) Antikörper (Cy7)
| Antigen |
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| Synonyme |
NUCLING, FLJ10128, KIAA1561, MGC141967, MGC141969 |
| Klonalität |
Polyklonal |
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Wirt
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Reaktivität
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Alternativen Human, Maus, Ratte (Rattus), Rind (Kuh), Pferd, Kaninchen
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Konjugat
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Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1)
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Applikation
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Alternativen Durchflusszytometrie (FACS), Immunfluoreszenz (IF)
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| Produktnummer |
ABIN717197 |
| Menge |
100 µg (1mg/1ml) |
| Preis |
290,60 € Zzgl. Versandkosten €20,00 und MWSt
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| Lieferung nach |
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| Verfügbarkeit |
Lieferung in 10 bis 15 Werktagen |
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Weitere Bezeichnung
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UACA
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Immunogen
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Polyclonal antibodies are produced by immunizing animals with synthetic peptide derived from human UACA
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Format
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Lyophilized
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Wiederherstellung
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Reconstitute with 100ul sterille distilled water. After reconstitution, stock concentration=1ug/1ul, preservatives included (BSA=10ug/ul, Sodium azide=0.1%)
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Isotyp
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IgG
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Beschreibung
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Synonym: Uaca, Kiaa1561, Conflict, Uveal autoantigen with coiled coil domains and ankyrin repeats, Uveal autoantigen with coiled-coil domains and ankyrin repeats, Nuclear membrane-binding protein, Nucling.
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Spezifität
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Excitation / Emission Wavelengths: 743nm/767nm
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Molekulargewicht
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156kDa
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Kommentare
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Regulates APAF1 expression and plays an important role in the regulation of stress-induced apoptosis. Promotes apoptosis by regulating three pathways apoptosome up-regulation LGALS3/galectin-3 down-regulation and NF-kappa-B inactivation.Regulates the redistribution of APAF1 into the nucleus after proapoptotic stress. Down-regulates the expression of LGALS3 by inhibiting NFKB1.Modulates isoactin dynamics to regulate the morphological alterations required for cell growth and motility.Interaction with ARF6 may modulate cell shape and motility after injury (By similarity).
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Applikationshinweise
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Flow-Cyt (1:50-200), IF (1:50-200)
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Konzentration
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1mg/1ml
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Reinigung
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Antibodies are purified by protein A and peptide affinity chromatography.
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Buffer
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Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
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Lagerung
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Ship at room temperature. Store at -20°C
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Beschränkungen
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Nur für Forschungszwecke einsetzbar
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Alternativen zu Antigen "UACA (UACA)", Typ "Antikörper" finden
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Wirte
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Kaninchen (22), Maus (2)
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Reaktivitäten
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Human (24), Maus (15), Rind (Kuh) (14), Pferd (14), Kaninchen (14), Ratte (Rattus) (14)
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Applikationen
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Durchflusszytometrie (FACS) (18), Immunfluoreszenz (IF) (17), Immunpräzipitation (IP) (5), Western Blot (WB) (5), ELISA (3), Immunhistochemie (Paraffinschnitte) (IHC (p)) (3), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)) (2), ELISA (Detektionsantikörper) (1), Immunoelectron Microscopy (IEM) (1), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (1)
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Konjugate
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Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1)
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