PRKAA1 Antikörper (pThr198) (Cy3)

Produktnummer ABIN711239

Der Kaninchen Polyklonal anti-PRKAA1 Antikörper wird verwendet zum Nachweis von PRKAA1 in Proben von Human, Maus, Ratte und Hund. Er wurde validiert für WB, FACS, IF (cc) und IF (p).

Kurzübersicht für PRKAA1 Antikörper (pThr198) (Cy3) (ABIN711239)

Target: PRKAA1 (Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1))

Reaktivität: Human, Maus, Ratte, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PRKAA1 Antikörper ist konjugiert mit Cy3

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-PRKAA1 Antikörper (Cy3)

Bindungsspezifität: pThr198

Kreuzreaktivität: Hund, Human, Maus, Ratte

Homologie: Cow,Sheep,Pig,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human PRKAA1 around the phosphorylation site of Thr198

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu PRKAA1

Target: PRKAA1 (Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1))

Andere Bezeichnung: AMPK alpha-1

Hintergrund:

Synonyms: AMPK alpha 1 + AMPK alpha 2 phospho S485 + S491, PRKAA1phospho S79, 5 AMP activated protein kinase alpha 1catalytic subunit, 5 AMP activated protein kinase catalytic alpha 1 chain, 5' AMP activated protein kinase catalytic subunit alpha 1, AAPK1,acetyl CoA carboxylase kinase,AI194361 antibody AI450832 ,AL024255 ,AMP -activate kinase alpha 1 subunit,AMP-activated protein kinase, catalytic, alpha -1,AMPK 1,AMPK alpha 1 chain,AMPK antibody AMPK1, AMPKa1,AMPKalpha1,C130083N04Rik,cb116 antibody EC 2.7.11.1, HMG CoA reductase kinase,hormone sensitive lipase kinase,im:7154392 antibody kinase AMPK alpha1 ,MGC33776,MGC57364 antibody PRKAA 1,PRKAA1,Protein kinase AMP activated alpha 1 catalytic subunit, SNF1-like protein AMPK,wu:fa94C10.

Background: The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq].

Molekulargewicht: 63kDa

Gen-ID: 5562

Pathways: AMPK Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Warburg Effekt