PCSK7 Antikörper (C-Term)

Produktnummer ABIN657966

Der Kaninchen Polyklonal anti-PCSK7 Antikörper (Klon RB34092) (ABIN657966) detektiert spezifisch PCSK7 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für PCSK7 Antikörper (C-Term) (ABIN657966)

Target: PCSK7 (Proprotein Convertase Subtilisin/kexin Type 7 (PCSK7))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PCSK7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB34092

Produktdetails anti-PCSK7 Antikörper

Bindungsspezifität: AA 692-721, C-Term

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PCSK7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 692-721 amino acids from the C-terminal region of human PCSK7.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: PCSK7 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Haltbarkeit: 6 months

Details zu PCSK7

Target: PCSK7 (Proprotein Convertase Subtilisin/kexin Type 7 (PCSK7))

Andere Bezeichnung: PCSK7

Hintergrund: The protein encoded by this gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein is a calcium-dependent serine endoprotease. It is structurally related to its family members, PACE and PACE4. This protein is concentrated in the trans-Golgi network, associated with the membranes, and is not secreted. It can process proalbumin and is thought to be responsible for the activation of HIV envelope glycoproteins gp160 and gp140. This gene has been implicated in the transcriptional regulation of housekeeping genes. Multiple alternatively spliced transcripts are described for this gene but their full length nature is not yet known. Downstream of this gene's map location at 11q23-q24, nucleotides that match part of this gene's 3' end are duplicated and inverted. A translocation breakpoint associated with lymphoma occurs between this gene and its inverted counterpart.

Molekulargewicht: 86247

Gen-ID: 9159

NCBI Accession: NP_004707

UniProt: Q16549