ACVR1 Antikörper (AA 132-161)

Produktnummer ABIN657777

Der Kaninchen Polyklonal anti-ACVR1 Antikörper (Klon RB33883) (ABIN657777) detektiert spezifisch ACVR1 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für ACVR1 Antikörper (AA 132-161) (ABIN657777)

Target: ACVR1 (ACRV1) (Activin Receptor Type I (ACRV1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ACVR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB33883

Produktdetails anti-ACVR1 Antikörper

Bindungsspezifität: AA 132-161

Homologie: B, M, Rat

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ACVR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 132-161 amino acids from the Central region of human ACVR1.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. WB: 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: ACVR1 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Haltbarkeit: 6 months

Details zu ACVR1

Target: ACVR1 (ACRV1) (Activin Receptor Type I (ACRV1))

Andere Bezeichnung: ACVR1

Hintergrund: Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I ( I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling, and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. This gene encodes activin A type I receptor which signals a particular transcriptional response in concert with activin type II receptors. Mutations in this gene are associated with fibrodysplasia ossificans progressive.

Molekulargewicht: 57153

Gen-ID: 90

NCBI Accession: NP_001096, NP_001104537

UniProt: Q04771