Nibrin Antikörper (C-Term)

Produktnummer ABIN655721

Der Kaninchen Polyklonal anti-Nibrin Antikörper wird verwendet zum Nachweis von Nibrin in Proben von Human. Er wurde validiert für WB, IF und FACS.

Kurzübersicht für Nibrin Antikörper (C-Term) (ABIN655721)

Target: Nibrin (NBN)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Nibrin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

Klon: RB19072

Produktdetails anti-Nibrin Antikörper

Bindungsspezifität: AA 602-630, C-Term

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This NBN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 602-630 amino acids from the C-terminal region of human NBN.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: IF: 1:10~50. WB: 1:1000. FC: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu Nibrin

Target: Nibrin (NBN)

Andere Bezeichnung: NBN

Hintergrund: Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation.

Molekulargewicht: 84959

Gen-ID: 4683

NCBI Accession: NP_002476

UniProt: O60934

Pathways: DNA Reparatur, Production of Molecular Mediator of Immune Response