FCGR1A Antikörper
Kurzübersicht für FCGR1A Antikörper (ABIN6253925)
Target
Alle FCGR1A Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Spezifität
- CD64 reacts with the Fc gamma receptor 1 (FcγR1), a glycoprotein with a molecular weight of 72 kDa. The antigen is a high-affinity receptor for IgG and is able to bind human IgG1 and IgG3. The antigen is expressed on macrophages, monocytes, and interferon γ (IFN-γ) and Granulocyte Colony Stimulating Factor (G-CSF) stimulated neutrophils.
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Aufreinigung
- Ion exchange column
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Isotyp
- IgG1
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Lagerung
- 4 °C
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- FCGR1A (Fc Fragment of IgG, High Affinity Ia, Receptor (CD64) (FCGR1A))
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Andere Bezeichnung
- CD64
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Hintergrund
- Antigen distribution: This antibody binds to a CD64 epitope distinct from the ligand-binding site and from the clone 32.2 antibody to CD64 epitope. It shows especially high affinity binding to human mononuclear phagocytes and polymorphonuclear leukocytes exposed to IFN-γ or G-CSF. Its binding is not blocked in the presence of human IgG or immune complexes. Cellular Expression: Fc gamma receptor 1 on macrophages, monocytes and neutrophils.
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Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
Target
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