Cysteine-Rich Secretory Protein 3 (CRISP3) Antikörper

Antigen: Cysteine-Rich Secretory Protein 3 (CRISP3)

Synonyme: Aeg2, CRS3, SGP28, CRISP-3, aln-a, crisp3, MGC76177, CRISP3, CRISP2, HSP-3, MGC126588, dJ442L6.3

Klonalität: Monoklonal (LV-2A2)

Wirt: Maus

Reaktivität: Human

Applikation: Durchflusszytometrie (FACS), Zell-ELISA (cELISA)

Produktnummer: ABIN648781

Produktbeschreibung

Weitere Bezeichnung: CRISP3

Swiss-Prot: P54108

Immunogen: anti-human cysteine-rich secretory protein 3 (Crisp3, SGP28), Genetic immunisation with cDNA encoding human Crisp3

Format: Purified

Isotyp: IgG1  (Passende Sekundärantikörper)

Klon: LV-2A2

Beschreibung: Cysteine-rich secretory protein 3 (CRISP3) belongs to the cysteine-rich secretory protein family. CRISPs are characterized by a cysteine-rich domain at the COOH terminal that form 8 intramolecular disulfide bonds (1). Mammalian members of the CRISP family are expressed predominantly in the male reproductive tract and are implicated in the process of reproduction from spermiogenesis, posttesticular sperm maturation and capacitation to oocyte-sperm fusion (2). CRISP3 is epithelium-specific and found predominantly in salivary gland, pancreas and prostate, and in less abundance in the epididymis, ovary, thymus and colon. CRISP3 is up-regulated in malignant prostatic epithelium, therefore, it can be used as a potential prostate cancer biomarker (3).

Spezifität: FACS,Cell-ELISA

Anwendungen

Applikationshinweise: Flow cytometry: 1.2 µg/10 6 cells. CELISA: 1:200 - 1:400. For each application a titration should be performed to determine the optimal concentration.

Konzentration: 2mg/ml

Reinigung: Protein G

Buffer: phosphate buffered saline, pH 7.2

Lagerung: short term: 2°C - 8°C

Beschränkungen: Nur für Forschungszwecke einsetzbar

Publikationen

Publikationen: F: F: in: Von den Autoren verwendete Methode: F (1:F, Probematerial (Species): F). Weitere Details: F