HCV Core Protein Antikörper (AA 1-120)

Produktnummer ABIN640223

Der Ziege not_set anti-HCV Core Protein Antikörper wird verwendet zum Nachweis von HCV Core Protein in Proben von Hepatitis C Virus (HCV). Er wurde validiert für WB und ELISA.

Kurzübersicht für HCV Core Protein Antikörper (AA 1-120) (ABIN640223)

Target: HCV Core Protein (HCV C) (Hepatitis C Virus Core Protein (HCV C))

Reaktivität: Hepatitis C Virus (HCV)

Wirt: Ziege

Konjugat: Dieser HCV Core Protein Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-HCV Core Protein Antikörper

Bindungsspezifität: AA 1-120

Spezifität: Hepatitis C Virus Core antigen (amino acids 1-120)

Produktmerkmale: Goat Anti-Hepatitic C Virus (HCV) Core Antigen (aa 1-120)

Aufreinigung: Purified

Immunogen: Recombinant HCV Core Antigen (genotype 1a)

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 4-5 mg/ml (OD280nm, E^0.1% = 1.4)

Buffer: 0.01M PBS, pH 7.2

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Details zu HCV Core Protein

Target: HCV Core Protein (HCV C) (Hepatitis C Virus Core Protein (HCV C))

Substanzklasse: Viral Protein

Hintergrund: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymesubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). Ube2L3 gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is demonstrated to participate in the ubiquitination of p53, c-Fos, and the NF-kB precursor p105 in vitro. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. It catalyzes the covalent attachment of ubiquitin to other proteins and mediates the selective degradation of short-lived and abnormal proteins as well as playing a role in the E6/E6-AP-induced ubiquitination of p53/TP53. Expression is ubiquitous, with highest expression in testis.