beta-Site APP-Cleaving Enzyme 1 (BACE) Antikörper

Antigen: beta-Site APP-Cleaving Enzyme 1 (BACE)

Synonyme: ASP2, BACE, HSPC104, FLJ90568, KIAA1149, C76936, Bace, bace1, MGC77409, BACE1, MGC137940, MGC145931, Bace1, ASP1, BAE2, DRAP, AEPLC, ALP56, ASP21, CDA13, CEAP1, ARP1, AI850424, 1110059C24Rik, bace2, MGC68881, MGC68482, BACE2

Klonalität: Polyklonal

Wirt: Kaninchen

Applikation: Immunhistochemie (Paraffinschnitte) (IHC (p))

Produktnummer: ABIN636992

Produktbeschreibung

Weitere Bezeichnung: BACE1

Immunogen: BACE1 antibody was raised in rabbit using a synthetic peptide conjugated to KLH as the immunogen.

Beschreibung: Beta-site APP cleaving enzyme 1 (BACE1) is an enzyme that in humans is encoded by the BACE1 gene. Beta-Secretase is an aspartic-acid protease important in the pathogenesis of Alzheimer's disease, and in the formation of myelin sheaths in peripheral nerve cells. The transmembrane protein contains two active site aspartate residues in its extracellular protein domain and may function as a dimer.

Synonyme: ASP2, BACE, HSPC104, FLJ90568, KIAA1149, C76936, Bace, bace1, MGC77409, BACE1, MGC137940, MGC145931, Bace1, ASP1, BAE2, DRAP, AEPLC, ALP56, ASP21, CDA13, CEAP1, ARP1, AI850424, 1110059C24Rik, bace2, MGC68881, MGC68482, BACE2

Anwendungen

Konzentration: 1.0 mg/ml

Reinigung: BACE1 antibody was purified by affinity chromatography.

Buffer: Purified by Immunoaffinity Chromatography and supplied in PBS with 0.1% NaN3.

Lagerung: Store at 4 °C for short term storage. Aliquot and store at -70 °C for long term storage. Avoid repeated freeze/thaw cycles.

Forschungsgebiet: Proteolyse / Ubiquitin, Alzheimer-Krankheit (Morbus Alzheimer), Enzyme