Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein 1 (AIMP1) Antikörper

Antigen: Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein 1 (AIMP1)

Synonyme: p43, SCYE1, MGC128105, MGC154081, wu:fa95a05, zgc:154081, AIMP1, EMAP2, EMAPII

Klonalität: Polyklonal

Wirt: Ziege

Applikation: ELISA, Blockierende Antikörper (Inhibition), Western Blot (WB)

Produktnummer: ABIN636614

Produktbeschreibung

Weitere Bezeichnung: EMAP II

Immunogen: EMAP II antibody was raised in goat using highly pure recombinant human EMAP-II as the immunogen.

Beschreibung: EMAP-II is a tumor derived cytokine that exerts a wide range of activities on endothelial cells, monocytes and neutrophils. EMAP-II inhibits endothelial cell proliferation, vasculogenesis, neovessel formation, and can induce apoptosis. It is also chemotactic towards neutrophils and monocytes and induces myeloperoxidase activity from neutrophils. Of clinical importance, EMAP-II inhibits angiogenesis of vascular beds and suppresses the growth of primary and secondary tumors without affecting normal tissues. Mature EMAP-II is an 18.3 kDa protein, which is synthesized as the C-terminal portion of a biologically inactive precursor protein containing a propeptide of 146 amino acid residues.

Molekulargewicht: 18.3 kDa (predicted detection band MW)

Anwendungen

Reinheit: Affinity Purified

Buffer: Lyophilized from PBS, pH 7.2.

Lagerung: Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C. Avoid repeated freeze/thaw cycles.

Forschungsgebiet: Krebs, DNS/RNS, Angeborene Immunität, Angiogenese, Apoptose/Nekrose