PABPC4 Antikörper (Middle Region)

Produktnummer ABIN633447

Der Kaninchen Polyklonal anti-PABPC4 Antikörper (ABIN633447) detektiert spezifisch PABPC4 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für PABPC4 Antikörper (Middle Region) (ABIN633447)

Target: PABPC4 (Poly(A) Binding Protein, Cytoplasmic 4 (Inducible Form) (PABPC4))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PABPC4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PABPC4 Antikörper

Bindungsspezifität: Middle Region

Spezifität: PABPC4 antibody was raised against the middle region of PABPC4

Aufreinigung: Affinity purified

Immunogen: PABPC4 antibody was raised using the middle region of PABPC4 corresponding to a region with amino acids RPNPRWQQGGRPQGFQGMPSAIRQSGPRPTLRHLAPTGSECPDRLAMDFG

Anwendungsinformationen

Applikationshinweise: WB: 0.5 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

PABPC4 Blocking Peptide, (ABIN5615185), is also available for use as a blocking control in assays to test for specificity of this PABPC4 antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Lyophilized powder. Add distilled water for a 1 mg/mL concentration of PABPC4 antibody in PBS

Konzentration: Lot specific

Buffer: PBS

Handhabung: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.

Details zu PABPC4

Target: PABPC4 (Poly(A) Binding Protein, Cytoplasmic 4 (Inducible Form) (PABPC4))

Andere Bezeichnung: PABPC4

Hintergrund: Poly(A)-binding proteins (PABPs) bind to the poly(A) tail present at the 3-prime ends of most eukaryotic mRNAs. PABPC4 or IPABP (inducible PABP) was isolated as an activation-induced T-cell mRNA encoding a protein. Activation of T cells increased PABPC4 mRNA levels in T cells approximately 5-fold. PABPC4 contains 4 RNA-binding domains and proline-rich C terminus. PABPC4 is localized primarily to the cytoplasm. It is suggested that PABPC4 might be necessary for regulation of stability of labile mRNA species in activated T cells. PABPC4 was also identified as an antigen, APP1 (activated-platelet protein-1), expressed on thrombin-activated rabbit platelets.

Molekulargewicht: 71 kDa (MW of target protein)

Pathways: SARS-CoV-2 Protein Interaktom