Liver Arginase Antikörper (AA 1-145)
Kurzübersicht für Liver Arginase Antikörper (AA 1-145) (ABIN615799)
Target
Alle Liver Arginase (ARG1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1-145
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Spezifität
- This antibody recognizes Arginase I.
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Kreuzreaktivität (Details)
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Species reactivity (expected):Mouse (85 %), Rat (83 %), Rabbit (90 %), Bovine (89 %), Pig (90 %).
Species reactivity (tested):Human. -
Aufreinigung
- Immunoaffinity Chromatography
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Immunogen
- Recombinant protein fragment containing a sequence corresponding to a region within amino acids 1 and 145 of Human Arginase-1. Genename: ARG1
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1.0 mg/mL
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Buffer
- 0.1 M Tris-glycine, pH 7.0, 0.01 % Thimerosal, 10 % Glycerol
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Konservierungsmittel
- Thimerosal (Merthiolate)
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Vorsichtsmaßnahmen
- This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store the antibody (in aliquots) at -20 °C.
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- Liver Arginase (ARG1) (Arginase, Liver (ARG1))
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Andere Bezeichnung
- Arginase-1
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Hintergrund
- Arginase-1 (ARG1) catalyzes the hydrolysis of L-arginine into ornithine and urea, a critical step for the urea cycle. Defects in ARG1 are the cause of argininemia, an autosomal recessive disorder characterized by hyperammonemia. There are several isoforms of mammalian arginase. The type I isoform, is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Hepatocellular carcinoma usually shows higher protein expression of ARG1 than normal liver cells.Synonyms: ARG1, Liver-type arginase, Type I arginase
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Gen-ID
- 383
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NCBI Accession
- NP_000036
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UniProt
- P05089
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Pathways
- Cellular Response to Molecule of Bacterial Origin
Target
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