ATP6V1B2 Antikörper (AA 1-511)

Produktnummer ABIN560004

Zitiert in 2+ Publikationen. Der Maus Monoklonal anti-ATP6V1B2 Antikörper (Klon M1) (ABIN560004) detektiert spezifisch ATP6V1B2 in ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für ATP6V1B2 Antikörper (AA 1-511) (ABIN560004)

Target: ATP6V1B2 (ATPase, H+ Transporting, Lysosomal 56/58kDa, V1 Subunit B2 (ATP6V1B2))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ATP6V1B2 Antikörper ist unkonjugiert

Applikation: ELISA

Klon: M1

Produktdetails anti-ATP6V1B2 Antikörper

Bindungsspezifität: AA 1-511

Verwendungszweck: Mouse monoclonal antibody raised against a full length recombinant ATP6V1B2.

Sequenz: MALRAMRGIV NGAAPELPVP TGGPAVGARE QALAVSRNYL SQPRLTYKTV SGVNGPLVIL DHVKFPRYAE IVHLTLPDGT KRSGQVLEVS GSKAVVQVFE GTSGIDAKKT SCEFTGDILR TPVSEDMLGR VFNGSGKPID RGPVVLAEDF LDIMGQPINP QCRIYPEEMI QTGISAIDGM NSIARGQKIP IFSAAGLPHN EIAAQICRQA GLVKKSKDVV DYSEENFAIV FAAMGVNMET ARFFKSDFEE NGSMDNVCLF LNLANDPTIE RIITPRLALT TAEFLAYQCE KHVLVILTDM SSYAEALREV SAAREEVPGR RGFPGYMYTD LATIYERAGR VEGRNGSITQ IPILTMPNDD ITHPIPDLTG YITEGQIYVD RQLHNRQIYP PINVLPSLSR LMKSAIGEGM TRKDHADVSN QLYACYAIGK DVQAMKAVVG EEALTSDDLL YLEFLQKFER NFIAQGPYEN RTVFETLDIG WQLLRIFPKE MLKRIPQSTL SEFYPRDSAK H

Kreuzreaktivität: Human

Produktmerkmale: Antibody Reactive Against Recombinant Protein.

Immunogen: ATP6V1B2 (AAH03100, 1 a.a. ~ 511 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1x PBS, pH 7.4

Handhabung: Aliquot to avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Referenzen für anti-ATP6V1B2 Antikörper (ABIN560004)

Eriksson, Joosten, Roberg, Ollinger: "The histone deacetylase inhibitor trichostatin A reduces lysosomal pH and enhances cisplatin-induced apoptosis." in: Experimental cell research, Vol. 319, Issue 1, pp. 12-20, (2012) (PubMed).

Nilsson, Roberg, Grafström, Ollinger: "Intrinsic differences in cisplatin sensitivity of head and neck cancer cell lines: Correlation to lysosomal pH." in: Head & neck, Vol. 32, Issue 9, pp. 1185-94, (2010) (PubMed).

Details zu ATP6V1B2

Target: ATP6V1B2 (ATPase, H+ Transporting, Lysosomal 56/58kDa, V1 Subunit B2 (ATP6V1B2))

Andere Bezeichnung: ATP6V1B2

Hintergrund: Full Gene Name: ATPase, H+ transporting, lysosomal 56/58 kDa, V1 subunit B2
Synonyms: ATP6B1B2,ATP6B2,HO57,VATB,VPP3,Vma2

Gen-ID: 526

Pathways: Transition Metal Ion Homeostasis, Proton Transport