SHC3 Antikörper (Middle Region)

Produktnummer ABIN504133

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch SHC3 in WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd und Kaninchen.

Kurzübersicht für SHC3 Antikörper (Middle Region) (ABIN504133)

Target: SHC3 (SHC (Src Homology 2 Domain Containing) Transforming Protein 3 (SHC3))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SHC3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-SHC3 Antikörper

Bindungsspezifität: Middle Region

Sequenz: RLKPRPHAPD TAQFAGKEQT YYQGRHLGDT FGEDWQQTPL RQGSSDIYST

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against SHC3. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SHC3

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 594 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu SHC3

Target: SHC3 (SHC (Src Homology 2 Domain Containing) Transforming Protein 3 (SHC3))

Andere Bezeichnung: SHC3

Hintergrund: SHC3 is a signaling adapter that couples activated growth factor receptors to signaling pathway in neurons. SHC3 is involved in the signal transduction pathways of neurotrophin-activated Trk receptors in cortical neurons.
Alias Symbols: N-Shc, NSHC, SHCC, RAI
Protein Interaction Partner: KRT40, KRT31, GOLGA2, ERBB3, ERBB2, EGFR, SH3GL3, ARHGAP32, NTRK2, NTRK1, RET, FLT4, AXL, GRB2, ALK, APP,
Protein Size: 594

Molekulargewicht: 64 kDa

Gen-ID: 53358

NCBI Accession: NM_016848, NP_058544

UniProt: Q92529

Pathways: RTK Signalweg, EGFR Signaling Pathway, Neurotrophin Signalübertragung