EIF2S3 Antikörper (N-Term)

Produktnummer ABIN502695

Der Kaninchen Polyklonal anti-EIF2S3 Antikörper (ABIN502695) detektiert spezifisch EIF2S3 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Ratte, Maus, Hund, Rind (Kuh), Meerschweinchen, Pferd und Kaninchen.

Kurzübersicht für EIF2S3 Antikörper (N-Term) (ABIN502695)

Target: EIF2S3 (Eukaryotic Translation Initiation Factor 2, Subunit 3 Gamma, 52kDa (EIF2S3))

Reaktivität: Human, Ratte, Maus, Hund, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EIF2S3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-EIF2S3 Antikörper

Bindungsspezifität: N-Term

Sequenz: AGGEAGVTLG QPHLSRQDLT TLDVTKLTPL SHEVISRQAT INIGTIGHVA

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against EIF2S3. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human EIF2S3

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 472 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu EIF2S3

Target: EIF2S3 (Eukaryotic Translation Initiation Factor 2, Subunit 3 Gamma, 52kDa (EIF2S3))

Andere Bezeichnung: EIF2S3

Hintergrund: EIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B.
Alias Symbols: EIF2, EIF2G, EIF2gamma, eIF-2gA
Protein Interaction Partner: UBC, RNF2, rev, CCAR2, PLD3, EEF1E1, AIMP1, AIP, IQGAP1, RARS, QARS, IMPDH2, DNAJA1, EIF2S1, MAPK6, TARDBP, FN1, UBD, GRK5, CAND1, CDK2, SUMO1, ELAVL1, SUMO2, NDRG1, RAD21, HDGF, DCC, METAP2, EIF1B, CASP4, H3F3A, CTCF,
Protein Size: 472

Molekulargewicht: 51 kDa

Gen-ID: 1968

NCBI Accession: NM_001415, NP_001406

UniProt: P41091