HERC6 Antikörper (N-Term)

Produktnummer ABIN502366

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch HERC6 in WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Rind (Kuh), Pferd, Schwein, Kaninchen, Hund und Meerschweinchen.

Kurzübersicht für HERC6 Antikörper (N-Term) (ABIN502366)

Target: HERC6 (HECT and RLD Domain Containing E3 Ubiquitin Protein Ligase Family Member 6 (HERC6))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Pferd, Schwein, Kaninchen, Hund, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HERC6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-HERC6 Antikörper

Bindungsspezifität: N-Term

Sequenz: LSKDSQVFSW GKNSHGQLGL GKEFPSQASP QRVRSLEGIP LAQVAAGGAH

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against HERC6. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human HERC6

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 1022 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu HERC6

Target: HERC6 (HECT and RLD Domain Containing E3 Ubiquitin Protein Ligase Family Member 6 (HERC6))

Andere Bezeichnung: HERC6

Hintergrund: HERC6 belongs to the HERC family of ubiquitin ligases, all of which contain a HECT domain and at least 1 RCC1 (MIM 179710)-like domain (RLD). The 350-amino acid HECT domain is predicted to catalyze the formation of a thioester with ubiquitin before transferring it to a substrate, and the RLD is predicted to act as a guanine nucleotide exchange factor for small G proteins (Hochrainer et al., 2005 [PubMed 15676274]).
Alias Symbols: FLJ20637
Protein Interaction Partner: FUS, UBC, HSP90AA1, UBQLN2, HERC4, HERC3, NME2,
Protein Size: 1022

Molekulargewicht: 115 kDa

Gen-ID: 55008

NCBI Accession: NM_017912, NP_060382

UniProt: Q8IVU3