HERC6 Antikörper (N-Term)
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- Target Alle HERC6 Antikörper anzeigen
- HERC6 (HECT and RLD Domain Containing E3 Ubiquitin Protein Ligase Family Member 6 (HERC6))
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Bindungsspezifität
- N-Term
- Reaktivität
- Human, Maus, Ratte, Rind (Kuh), Pferd, Schwein, Kaninchen, Hund, Meerschweinchen
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser HERC6 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- LSKDSQVFSW GKNSHGQLGL GKEFPSQASP QRVRSLEGIP LAQVAAGGAH
- Homologie
- Cow: 100%, Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 93%
- Produktmerkmale
- This is a rabbit polyclonal antibody against HERC6. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human HERC6
- Top Product
- Discover our top product HERC6 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 1022 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- HERC6 (HECT and RLD Domain Containing E3 Ubiquitin Protein Ligase Family Member 6 (HERC6))
- Andere Bezeichnung
- HERC6 (HERC6 Produkte)
- Synonyme
- 1700121D12Rik antikoerper, 2510038N07Rik antikoerper, 4930427L17Rik antikoerper, AI451296 antikoerper, CEB1 antikoerper, Herc5 antikoerper, HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 antikoerper, hect domain and RLD 6 antikoerper, HERC6 antikoerper, Herc6 antikoerper
- Hintergrund
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HERC6 belongs to the HERC family of ubiquitin ligases, all of which contain a HECT domain and at least 1 RCC1 (MIM 179710)-like domain (RLD). The 350-amino acid HECT domain is predicted to catalyze the formation of a thioester with ubiquitin before transferring it to a substrate, and the RLD is predicted to act as a guanine nucleotide exchange factor for small G proteins (Hochrainer et al., 2005 [PubMed 15676274]).
Alias Symbols: FLJ20637
Protein Interaction Partner: FUS, UBC, HSP90AA1, UBQLN2, HERC4, HERC3, NME2,
Protein Size: 1022 - Molekulargewicht
- 115 kDa
- Gen-ID
- 55008
- NCBI Accession
- NM_017912, NP_060382
- UniProt
- Q8IVU3
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