PIAS1 Antikörper (Middle Region)

Produktnummer ABIN501787

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch PIAS1 in WB. Es zeigt Reaktivität gegenüber Proben von Human, Pferd, Rind (Kuh) und Hund.

Kurzübersicht für PIAS1 Antikörper (Middle Region) (ABIN501787)

Target: PIAS1 (Protein Inhibitor of Activated STAT, 1 (PIAS1))

Reaktivität: Human, Pferd, Rind (Kuh), Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PIAS1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PIAS1 Antikörper

Bindungsspezifität: Middle Region

Sequenz: LPTTNGSSSG SNSSLVSSNS LRESHSHTVT NRSSTDTASI FGIIPDIISL

Homologie: Cow: 79%, Dog: 93%, Horse: 79%, Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against PIAS1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PIAS1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 651 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PIAS1

Target: PIAS1 (Protein Inhibitor of Activated STAT, 1 (PIAS1))

Andere Bezeichnung: PIAS1

Hintergrund: PIAS1 is a member of the mammalian PIAS [protein inhibitor of activated STAT-1 (signal transducer and activator of transcription-1)] family. This member contains a putative zinc-binding motif and a highly acidic region. It inhibits STAT1-mediated gene act
Alias Symbols: DDXBP1, GBP, GU/RH-II, MGC141878, MGC141879, ZMIZ3
Protein Interaction Partner: STAT1, TRIM63, TRIM55, CEP250, PRDM1, SUMO1, L3MBTL2, CBS, SHFM1, SUMO2, SUMO3, SOX2, CHUK, SPOP, YWHAZ, UBC, SKIL, SGTA, ATXN1, SMAD7, SMAD4, SMAD1, HTT, PRPF40A, PPP1CC, BARD1, PAXIP1, NR1H2, PPARGC1A, NR1H3, PPARGC1B, RAD54L2, ZMYND11, UBD, PLAG1, MYB,
Protein Size: 651

Molekulargewicht: 72 kDa

Gen-ID: 8554

NCBI Accession: NM_016166, NP_057250

UniProt: O75925

Pathways: JAK-STAT Signalweg, Interferon-gamma Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Muscle Cell Differentiation, Hepatitis C