FANCL Antikörper (Internal Region)
Kurzübersicht für FANCL Antikörper (Internal Region) (ABIN499127)
Target
Alle FANCL Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Internal Region
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Sequenz
- C-QNLKDVLEID FP
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Spezifität
- This antibody is expected to recognize both isoforms (NP_001108108.1, NP_060532.2).
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Kreuzreaktivität (Details)
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Species reactivity (expected):Mouse, Rat, Canine, Bovine.
Species reactivity (tested):Human. -
Aufreinigung
- Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.
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Immunogen
- Peptide with sequence from the internal region of the protein sequence according to Human FANCL (NP_001108108.1 and NP_060532.2). Genename: FANCL
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Applikationshinweise
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Peptide ELISA: Limit Dilution: 1/16000. Western blot: 1-3 μg/mL. Detects a band of approx. 45 kDa in Human Bone Marrow lysates.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 0.5 mg/mL
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Buffer
- Tris saline, pH 7.3, 0.02 % Sodium Azide, 0.5 % BSA
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- FANCL (Fanconi Anemia, Complementation Group L (FANCL))
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Andere Bezeichnung
- FANCL
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Hintergrund
- FANCL is a ubiquitin ligase protein that mediates ubiquitination of FANCD2, a key step in the DNA damage pathway.Synonyms: E3 ubiquitin-protein ligase FANCL, FAAP43, Fanconi anemia group L protein, Fanconi anemia-associated polypeptide of 43 kDa, PHF9
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Molekulargewicht
- 43.4kDa (NP_001108108.1).
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Gen-ID
- 55120
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NCBI Accession
- NP_001108108
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UniProt
- Q9NW38
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Pathways
- DNA Reparatur
Target
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