UBA52 Antikörper (C-Term)

Produktnummer ABIN498041

Der Kaninchen Polyklonal anti-UBA52 Antikörper wird verwendet zum Nachweis von UBA52 in Proben von Human. Er wurde validiert für WB, IHC (p) und EIA.

Kurzübersicht für UBA52 Antikörper (C-Term) (ABIN498041)

Target: UBA52 (Ubiquitin A-52 Residue Ribosomal Protein Fusion Product 1 (UBA52))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UBA52 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails anti-UBA52 Antikörper

Bindungsspezifität: C-Term

Spezifität: Recognizes Ubiquitin, Ribosomal Protein L40 (UBA52).

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Protein G Chromatography

Immunogen: Synthetic peptide kLH conjugated synthetic peptide selected from the C-terminal region of Human Ubiquitin .Remarks: Antigen Modification: C-Terminus

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA: 1/50-1/100Western blot: 1/100-1/500Immunohistochemistry on Paraffin Sections: 10 μg/mL
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu UBA52

Target: UBA52 (Ubiquitin A-52 Residue Ribosomal Protein Fusion Product 1 (UBA52))

Andere Bezeichnung: UBA52

Hintergrund: This gene encodes ubiquitin, one of the most conserved proteins known. Ubiquitin is required for ATP-dependent, nonlysosomal intracellular protein degradation of abnormal proteins and normal proteins with a rapid turnover. Ubiquitin is covalently bound to proteins to be degraded, and presumably labels these proteins for degradation. Ubiquitin also binds to histone H2A in actively transcribed regions but does not cause histone H2A degradation, suggesting that ubiquitin is also involved in regulation of gene expression. This gene consists of three direct repeats of the ubiquitin coding sequence with no spacer sequence. Consequently, the protein is expressed as a polyubiquitin precursor with a final amino acid after the last repeat. Aberrant form of this protein has been noticed in patients with Alzheimer's and Down syndrome.Synonyms: CEP52, UBCEP2, Ubiquitin A-52 residue ribosomal protein fusion product 1, Ubiquitin-60S ribosomal protein L40

Gen-ID: 7311

NCBI Accession: NP_001029102

UniProt: P62987

Pathways: Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Activation of Innate immune Response, Mitotic G1-G1/S Phases, DNA Replication, Toll-Like Receptors Cascades, Synthesis of DNA, EGFR Downregulation