GNA15 Antikörper

Produktnummer ABIN488048

Der Kaninchen Polyklonal anti-GNA15 Antikörper wird verwendet zum Nachweis von GNA15 in Proben von Human, Maus, Ratte und Kaninchen. Er wurde validiert für WB.

Kurzübersicht für GNA15 Antikörper (ABIN488048)

Target: GNA15 (Guanine Nucleotide Binding Protein (G Protein), alpha 15 (Gq Class) (GNA15))

Reaktivität: Human, Maus, Ratte, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GNA15 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-GNA15 Antikörper

Spezifität: The antibody detects GA15 in samples from Human, Mouse, Rat, and Rabbit origins. It also detects GA16 from samples of Human origin.

Aufreinigung: Affinity Chromatography.

Immunogen: Synthetic peptide surrounding amino acid 356 of Human G Protein Alpha 15

Anwendungsinformationen

Applikationshinweise: Western blotting (0.5-4 μg/mL). From Researcher's feedback, the antibody can be used in Immunohistochemistry (5-20 μg/mL).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: PBS ( pH 7.2) containing 30 % Glycerol, 0.5 % BSA and 0.01 % Thimerosal as preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C/-80 °C

Informationen zur Lagerung: Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.

Details zu GNA15

Target: GNA15 (Guanine Nucleotide Binding Protein (G Protein), alpha 15 (Gq Class) (GNA15))

Andere Bezeichnung: G Protein alpha 15

Hintergrund: G Protein alpha 16 (GA16) is the only heterotrimeric G protein with a restricted expression pattern in hematopoietic cells. Differentiation of promyelocytic cells leads to decreased expression of GA16. The G protein is known to couple a large number of G protein-coupled receptors to PLC-beta and can lead to production of the secondary messengers diacylglycerol and inositol phosphates. Targeted deletion of GA15, a mouse orthologue of human GA16, causes reduced C5α receptor signaling. GA16 serves as a marker, in addition to CD34, for hematopoietic progenitor cells.Synonyms: G alpha-15, GNA15, GNA16, Guanine nucleotide-binding protein subunit alpha-15

Gen-ID: 2769

NCBI Accession: NP_002059

UniProt: P30679