Tacrolimus (FK506) Antikörper
Kurzübersicht für Tacrolimus (FK506) Antikörper (ABIN472100)
Target
Wirt
Klonalität
Konjugat
Applikation
Klon
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Spezifität
- Detects FK-506, a macrolide with similar but more potent immunosuppressant activity than cyclosporine. It is a 23-membered lactone produced by the bacteria Streptomyces tsukubaensis. FK-506 inhibits signal transduction and interleukin-2 transcription in CD4+ T helper lymphocytes, and is mainly used after allogeneic organ transplantation to reduce organ rejection. Side effects of FK-506 treatment include nephrotoxicity, neurotoxicity, diabetes mellitus and hypertension.
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Aufreinigung
- Purified
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Immunogen
- FK-506-BSA conjugate.
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Isotyp
- IgM
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Tris buffered saline, 0.09 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeat freeze-thaw cycles.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
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- Tacrolimus (FK506)
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Andere Bezeichnung
- FK506 / Tacrolimus
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Substanzklasse
- Chemical
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Hintergrund
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Name/Gene ID: FK506
Synonyms: FK506
Target
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