PKD1 Antikörper (AA 4289-4300)

Produktnummer ABIN462530

Der Ziege Polyklonal anti-PKD1 Antikörper wird verwendet zum Nachweis von PKD1 in Proben von Human. Er wurde validiert für IHC und IHC (p).

Kurzübersicht für PKD1 Antikörper (AA 4289-4300) (ABIN462530)

Target: PKD1 (Polycystic Kidney Disease 1 (Autosomal Dominant) (PKD1))

Reaktivität: Human

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser PKD1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-PKD1 Antikörper

Bindungsspezifität: AA 4289-4300

Spezifität: Human PKD1. This antibody is expected to recognize both reported isoforms (NP_001009944.1 and NP_000287.2).

Homologie: Percent identity by BLAST analysis: Human, Gorilla, Gibbon (100%) Marmoset, Panda, Cat, Dog, Horse (83%).

Aufreinigung: Immunoaffinity purified

Immunogen: Synthetic peptide C-RTPLRAKNKVHP from the C-terminus of human PKD1 (NP_001009944.1, NP_000287.2). Percent identity by BLAST analysis: Human, Gorilla, Gibbon (100%), Marmoset, Panda, Cat, Dog, Horse (83%).

Type of Immunogen: Synthetic peptide

Anwendungsinformationen

Applikationshinweise: Approved: IHC, IHC-P (3.75 μg/mL)

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 3.75 μg/mL.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Minimize freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze-thaw cycles.

Details zu PKD1

Target: PKD1 (Polycystic Kidney Disease 1 (Autosomal Dominant) (PKD1))

Andere Bezeichnung: PKD1 / Polycystin

Hintergrund: Name/Gene ID: PKD1

Synonyms: PKD1, PBP, Polycystin, TRPP1, Pc-1, Polycystin 1, Polycystin-1

Gen-ID: 5310

NCBI Accession: NP_001009944, NP_000287

UniProt: P98161

Pathways: Myometrial Relaxation and Contraction, Maintenance of Protein Location