PDGFRA Antikörper (PE)
Kurzübersicht für PDGFRA Antikörper (PE) (ABIN452288)
Target
Alle PDGFRA Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Spezifität
- The antibody recognizes CD140a / PDGF-RA, the 170 kDa alpha chain of platelet-derived growth factor receptor, which is widely expressed on a variety of mesenchymal-derived cells and plays pro-proliferative or anti-proliferative roles in various tumours.
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Kreuzreaktivität (Details)
- Species reactivity (tested):Human
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Produktmerkmale
- Synonyms: PDGF-R-alpha, PDGF Receptor alpha, Alpha-type platelet-derived growth factor receptor,CD140 antigen-like family member A
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Immunogen
- CD140a-transfected NIH 3T3 cells
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Isotyp
- IgG1
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anti-Platelet Derived Growth Factor Receptor alpha (PDGFRA) (AA 179-361) antibody
PDGFRA Reaktivität: Human ELISA, IHC, FACS Wirt: Maus Monoclonal 5B11G5 unconjugated
anti-Platelet Derived Growth Factor Receptor alpha (PDGFRA) (AA 698-727) antibodyPDGFRA Reaktivität: Maus WB, IHC (p) Wirt: Kaninchen Polyclonal RB11101 unconjugated
anti-Platelet Derived Growth Factor Receptor alpha (PDGFRA) (AA 361-528) antibodyPDGFRA Reaktivität: Human ELISA, FACS, ICC Wirt: Maus Monoclonal 8E12F2 unconjugated
anti-Platelet Derived Growth Factor Receptor alpha (PDGFRA) (AA 331-719) antibodyPDGFRA Reaktivität: Human WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Platelet Derived Growth Factor Receptor alpha (PDGFRA) (AA 1048-1077), (C-Term) antibodyPDGFRA Reaktivität: Human, Maus WB, FACS, IHC (p) Wirt: Kaninchen Polyclonal RB2005-2006 unconjugated
anti-Platelet Derived Growth Factor Receptor alpha (PDGFRA) (AA 179-361) antibodyPDGFRA Reaktivität: Human ELISA, FACS Wirt: Maus Monoclonal 1A10A8 unconjugated
anti-Platelet Derived Growth Factor Receptor alpha (PDGFRA) (AA 25-218) antibodyPDGFRA Reaktivität: Human WB, ELISA, PLA Wirt: Maus Monoclonal 4H1-1C9 unconjugated
anti-Platelet Derived Growth Factor Receptor alpha (PDGFRA) (AA 1-1089) antibodyPDGFRA Reaktivität: Human WB, PLA Wirt: Kaninchen Polyclonal unconjugated
anti-Platelet Derived Growth Factor Receptor alpha (PDGFRA) (AA 1035-1053) antibodyPDGFRA Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Huhn, Affe, Schwein, Pferd, Kaninchen, Xenopus laevis, Fledermaus, Hamster WB, IHC, IHC (p), IP Wirt: Kaninchen Polyclonal unconjugated
anti-Platelet Derived Growth Factor Receptor alpha (PDGFRA) (C-Term) antibodyPDGFRA Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Lagerung
- 4 °C
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Informationen zur Lagerung
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Store the antibody at 2 - 8 °C. DO NOT FREEZE! This product is photosensitive and should be protected from light.
Shelf life: one year from despatch. -
Haltbarkeit
- 12 months
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- PDGFRA (Platelet Derived Growth Factor Receptor alpha (PDGFRA))
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Andere Bezeichnung
- CD140a / PDGFRA
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Hintergrund
- CD140a / PDGF-RA (platelet-derived growth factor receptor alpha) is a cell surface receptor for members of platelet-derived growth factor family, whose intracellular part contains a tyrosine kinase domain. CD140a forms homodimers, or heterodimerizes with CD140b / PDGF-RB. Whereas CD140b induces in different cell types their proliferation and migration, the role of CD140a is more controversial, with pro-proliferative or anti-proliferative effects. CD140a has early developmental functions, mediates mesodermal cell migration, and later acts in signaling associated in epithelial-mesenchymal interactions.Synonyms: Alpha-type platelet-derived growth factor receptor, CD140 antigen-like family member A, PDGF Receptor alpha, PDGF-R-alpha
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Gen-ID
- 5156
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UniProt
- P16234
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Pathways
- RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Platelet-derived growth Factor Receptor Signaling
Target
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