GNAO1 Antikörper (Middle Region)
Kurzübersicht für GNAO1 Antikörper (Middle Region) (ABIN406520)
Target
Alle GNAO1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Middle Region
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Sequenz
- CDVVSRMEDT EPFSAELLSA MMRLWGDSGI QECFNRSREY QLNDSAKYYL
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Yeast: 100%, Zebrafish: 93%
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Produktmerkmale
- This is a rabbit polyclonal antibody against GNAO1. It was validated on Western Blot using a cell lysate as a positive control.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human GNAO1
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 354 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Identification of plasma biomarker candidates in glioblastoma using an antibody-array-based proteomic approach." in: Radiology and oncology, Vol. 48, Issue 3, pp. 257-66, (2014) (PubMed).
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- GNAO1 (Guanine Nucleotide Binding Protein (G Protein), alpha Activating Activity Polypeptide O (GNAO1))
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Andere Bezeichnung
- GNAO1
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Hintergrund
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Activated Goalpha interacted directly with PLZF, and enhanced its function as a transcriptional and cell growth suppressor. Goalpha might play a role in mediating extracellular signal-regulated kinase activation by G protein-coupled receptors in the brain.
Alias Symbols: DKFZp686O0962, G-ALPHA-o, GNAO
Protein Interaction Partner: UBC, ADRA2A, BAG3, Htt, RGS9, GABBR1, Haus4, RGS1, RIC8A, DCTN2, KLHL3, SCN8A, PDE6G, CRHR1, GPSM2, HRH4, NGB, S1PR5, RGS19, GRM6, FFAR2, TSHR, RGS5, RGS10, RGS7, RGS4, RGS16, RGS14, PTPRU, CCR5, NUCB1, PDE6H, CACNA1B, OPRM1, OPRD1, GNAO1, GNAI1, ADRA2C,
Protein Size: 354 -
Molekulargewicht
- 40 kDa
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Gen-ID
- 2775
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NCBI Accession
- NM_138736, NP_620073
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UniProt
- B3KP89
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Pathways
- G-protein mediated Events
Target
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