C4BPA Antikörper (Middle Region)

Produktnummer ABIN405406

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch C4BPA in WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für C4BPA Antikörper (Middle Region) (ABIN405406)

Target: C4BPA (Complement Component 4 Binding Protein, alpha (C4BPA))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser C4BPA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-C4BPA Antikörper

Bindungsspezifität: Middle Region

Sequenz: QVLTGKRLMQ CLPNPEDVKM ALEVYKLSLE IEQLELQRDS ARQSTLDKEL

Homologie: Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against C4BPA. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human C4BPA

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 597 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu C4BPA

Target: C4BPA (Complement Component 4 Binding Protein, alpha (C4BPA))

Andere Bezeichnung: C4BPA

Hintergrund: C4BPA is a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. Along with a single, unique beta-chain, seven identical alpha-chains encoded by this gene assemble into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. The genes encoding both alpha and beta chains are located adjacent to each other on human chromosome 1 in the regulator of complement activation gene cluster.This gene encodes a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. Along with a single, unique beta-chain, seven identical alpha-chains encoded by this gene assemble into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. The genes encoding both alpha and beta chains are located adjacent to each other on human chromosome 1 in the regulator of complement activation gene cluster. Two pseudogenes of this gene are also found in the cluster. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: C4BP, PRP
Protein Interaction Partner: FN1, FXYD6, GIT2, SMARCD1, LBP, GTF2I, PROS1, LRP1, APCS, C4B, BMPR2,
Protein Size: 597

Molekulargewicht: 62 kDa

Gen-ID: 722

NCBI Accession: NM_000715, NP_000706

UniProt: P04003

Pathways: Komplementsystem