FAP Antikörper (Internal Region)

Produktnummer ABIN401429

Der Kaninchen Polyklonal anti-FAP Antikörper wird verwendet zum Nachweis von FAP in Proben von Human, Maus und Ratte. Er wurde validiert für WB und EIA.

Kurzübersicht für FAP Antikörper (Internal Region) (ABIN401429)

Target: FAP (Fibroblast Activation Protein, alpha (FAP))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FAP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-FAP Antikörper

Bindungsspezifität: Internal Region

Spezifität: This antibody is known to react with Mouse FAP protein.

Kreuzreaktivität (Details): Species reactivity (expected):Rat, Human.
Species reactivity (tested):Mouse.

Aufreinigung: Immunoffinity Chromatography.

Immunogen: Synthetic peptide corresponding to an internal region of mouse FAP protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA: 1/100000. Western Blot: 1/500-1/2000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.65 mg/mL (by UV absorbance at 280 nm)

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Details zu FAP

Target: FAP (Fibroblast Activation Protein, alpha (FAP))

Andere Bezeichnung: Seprase / FAP

Hintergrund: Fibroblast Activation Protein (FAP) is expressed in the stroma of sites that are undergoing wound healing. In addition, it has recently been reported that FAP is expressed in the stroma of sites of metastatic disease. Inhibition of FAP may lead to a dramatic decrease in the number of metastatic osteosarcoma lung nodules. FAP exists as an inactive monomer and when activated forms homodimers or heterodimers with DPP4. Multiple isoforms of FAP are reported as alternative splicing products from a common gene.Synonyms: 170 kDa melanoma membrane-bound gelatinase, Fibroblast activation protein alpha, Integral membrane serine protease

Gen-ID: 14089

NCBI Accession: NP_032012

UniProt: P97321

Pathways: Tube Formation