HAX1 Antikörper (N-Term)

Produktnummer ABIN400856

Der Maus Monoklonal anti-HAX1 Antikörper wird verwendet zum Nachweis von HAX1 in Proben von Human. Er wurde validiert für WB und EIA.

Kurzübersicht für HAX1 Antikörper (N-Term) (ABIN400856)

Target: HAX1 (HCLS1 Associated Protein X-1 (HAX1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser HAX1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Klon: AT3C5

Produktdetails anti-HAX1 Antikörper

Bindungsspezifität: AA 1-279, N-Term

Spezifität: The antibody recognizes human HAX-1. Other species not tested.

Produktmerkmale: Synonyms: HAX-1, HS1BP1, HCLS1-associated protein X-1, HS1-associating protein X-1, HS1-bindingprotein 1

Aufreinigung: Protein-G affinity chromatography

Immunogen: Recombinant human HAX1 (1-279 aa) purified from E. coli

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: ELISA. Western blot (1: 1000 - 1: 2000).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.0 mg/mL

Buffer: PBS, pH 7.4, containing 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for up to two weeks or (in aliquots) at -20 °C or -70 °Cfor longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu HAX1

Target: HAX1 (HCLS1 Associated Protein X-1 (HAX1))

Andere Bezeichnung: HAX1

Hintergrund: HAX1 is known to associate with hematopoietic cell-specific Lyn substrate 1 (HS1), one of the substrates of receptor-coupled tyrosine kinases activated during clonal expansion and deletion in lymphoid cells. It also interacts with the product of the polycystic kidney disease 2 (PKD2) gene and with the F-actin-binding protein, cortactin. HAX1 is also reported to bind to hairpin structures in vimentin and DNA polymerase beta mRNAs, so may play a role in mRNA stability and transport. It may also function in promoting cell survival. Defects in HAX1 are the cause of autosomal recessive severe congenital neutropenia 3 (SCN3) also called Kostmann disease.Synonyms: HAX-1, HCLS1-associated protein X-1, HS1-associating protein X-1, HS1-binding protein 1, HS1BP1

Gen-ID: 10456

UniProt: O00165

Pathways: Regulation of Actin Filament Polymerization