MAD2L1 Antikörper

Produktnummer ABIN400793

Der Maus Monoklonal anti-MAD2L1 Antikörper wird verwendet zum Nachweis von MAD2L1 in Proben von Human. Er wurde validiert für WB und IP.

Kurzübersicht für MAD2L1 Antikörper (ABIN400793)

Target: MAD2L1 (MAD2 Mitotic Arrest Deficient-Like 1 (Yeast) (MAD2L1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser MAD2L1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP)

Klon: 17D10

Produktdetails anti-MAD2L1 Antikörper

Spezifität: This antibody is directed against MAD2L1 protein.

Produktmerkmale: Synonyms: Mitotic spindle assembly checkpoint protein MAD2A, MAD2

Aufreinigung: Affinity chromatography on Protein A

Immunogen: Full-length recombinant human MAD2L1 protein

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Western Blot: 1/200 - 1/2000. Immunoprecipitation.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL (by UV absorbance at 280 nm)

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store the antibody at -20 °C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu MAD2L1

Target: MAD2L1 (MAD2 Mitotic Arrest Deficient-Like 1 (Yeast) (MAD2L1))

Andere Bezeichnung: MAD2L1

Hintergrund: MAD2L1 (also called mitotic spindle assembly checkpoint protein, MAD2A, MAD2-like 1 and HsMAD2) is a component of the mitotic spindle assembly checkpoint monitors the process of kinetochore-spindle attachment and delays the onset of anaphase when this process is not complete. MAD2L1 inhibits the activity of the anaphase-promoting complex by sequestering CDC20 until all chromosomes are aligned at the metaphase plate. MAD2L1 is related to the MAD2L2 gene located on chromosome 1. This protein has a nuclear localization. A MAD2 pseudogene has been mapped to chromosome 14.Synonyms: MAD2, Mitotic spindle assembly checkpoint protein MAD2A

Gen-ID: 4085

UniProt: Q13257