DIO1 Antikörper (N-Term)
Kurzübersicht für DIO1 Antikörper (N-Term) (ABIN390946)
Target
Alle DIO1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 30-57, N-Term
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Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogen
- This DIO1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 30-57 amino acids from the N-terminal region of human DIO1.
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Isotyp
- Ig Fraction
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Applikationshinweise
- WB: 1:1000. WB: 1:2000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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Haltbarkeit
- 6 months
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- DIO1 (Deiodinase, Iodothyronine, Type I (DIO1))
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Andere Bezeichnung
- DIO1
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Hintergrund
- DIO1 is a thiol-requiring propylthiouracil-sensitive oxidoreductase. It activates thyroid hormone by converting the prohormone thyroxine (T4) by outer ring deiodination (ORD) to bioactive 3,3',5-triiodothyronine (T3). It also degrades both hormones by inner ring deiodination (IRD).
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Molekulargewicht
- 28924
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Gen-ID
- 1733
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NCBI Accession
- NP_000783, NP_001034804, NP_001034805, NP_998758
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UniProt
- P49895
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Pathways
- Hormone Activity
Target
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