Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

LC3B Antikörper (pThr12)

MAP1LC3B Reaktivität: Human DB Wirt: Kaninchen Polyclonal RB12679 unconjugated
Produktnummer ABIN389913
  • Target Alle LC3B (MAP1LC3B) Antikörper anzeigen
    LC3B (MAP1LC3B) (Microtubule-Associated Protein 1 Light Chain 3 beta (MAP1LC3B))
    Bindungsspezifität
    • 23
    • 15
    • 15
    • 12
    • 9
    • 8
    • 7
    • 7
    • 7
    • 6
    • 5
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pThr12
    Reaktivität
    • 134
    • 51
    • 36
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 123
    • 14
    • 7
    Kaninchen
    Klonalität
    • 129
    • 16
    Polyklonal
    Konjugat
    • 76
    • 14
    • 13
    • 10
    • 10
    • 10
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser LC3B Antikörper ist unkonjugiert
    Applikation
    • 89
    • 55
    • 52
    • 28
    • 24
    • 14
    • 13
    • 10
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    Dot Blot (DB)
    Homologie
    B
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This LC3B Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T12 of human LC3B.
    Klon
    RB12679
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product MAP1LC3B Primärantikörper
  • Applikationshinweise
    DB: 1:500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Mitroulis, Kourtzelis, Kambas, Rafail, Chrysanthopoulou, Speletas, Ritis: "Regulation of the autophagic machinery in human neutrophils." in: European journal of immunology, Vol. 40, Issue 5, pp. 1461-72, (2010) (PubMed).

  • Target
    LC3B (MAP1LC3B) (Microtubule-Associated Protein 1 Light Chain 3 beta (MAP1LC3B))
    Andere Bezeichnung
    LC3B (MAP1LC3B Produkte)
    Synonyme
    ATG8F antikoerper, LC3B antikoerper, MAP1A/1BLC3 antikoerper, MAP1LC3B-a antikoerper, Map1lc3 antikoerper, Mpl3 antikoerper, zbs559 antikoerper, 1010001C15Rik antikoerper, Atg8 antikoerper, LC3b antikoerper, zgc:56434 antikoerper, wu:fb60g11 antikoerper, map1lc3b antikoerper, MGC76283 antikoerper, MAP1LC3B antikoerper, microtubule associated protein 1 light chain 3 beta antikoerper, microtubule-associated protein 1 light chain 3 beta antikoerper, microtubule associated protein 1 light chain 3 beta L homeolog antikoerper, MAP1LC3B antikoerper, Map1lc3b antikoerper, map1lc3b antikoerper, map1lc3b.L antikoerper
    Hintergrund
    MAP1A and MAP1B are microtubule-associated proteins which mediate the physical interactions between microtubules and components of the cytoskeleton. These proteins are involved in formation of autophagosomal vacuoles (autophagosomes). MAP1A and MAP1B each consist of a heavy chain subunit and multiple light chain subunits. MAP1LC3b is one of the light chain subunits and can associate with either MAP1A or MAP1B. The precursor molecule is cleaved by APG4B/ATG4B to form the cytosolic form, LC3-I. This is activated by APG7L/ATG7, transferred to ATG3 and conjugated to phospholipid to form the membrane-bound form, LC3-II. Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole).
    Molekulargewicht
    14688
    Gen-ID
    81631
    NCBI Accession
    NP_073729
    UniProt
    Q9GZQ8
    Pathways
    Autophagie
Sie sind hier:
Kundenservice