BCL2-Related Protein A1 (BCL2A1) (BH3 Domain) Antikörper

Antigen: BCL2-Related Protein A1 (BCL2A1)

Synonyme: GRS, BFL1, ACC-1, ACC-2, HBPA1, BCL2L5, Bcl2a1, BCL2A1

Epitope: BH3 Domain

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Human

Applikation: Western Blot (WB), Immunhistochemie (IHC), ELISA

Zertifikate: ISO 9001:2008

Produktnummer: ABIN388092

Produktbeschreibung

Produktmerkmale: Purified Rabbit Polyclonal Antibody (Pab)

Weitere Bezeichnung: BCL2A1 (A1) (BH3 Domain Specific)

Gen-ID: 597

Swiss-Prot: Q16548

Immunogen: This BCL2A1 (A1) antibody was developed against a synthetic peptide selected from the N-terminal region of human BCL2-related protein A1, within the BH3 domain.

Isotyp: Ig  (Passende Sekundärantikörper)

Beschreibung: Other names: Human Bcl2-related Protein A1, BFL1, Hematopoietic-specific early response protein, GRS protein

Spezifität: This antibody was developed against a synthetic peptide selected from the N-terminal region of human BCL2-related protein A1, within the BH3 domain.

Molekulargewicht: 20132 DA

Anwendungen

Applikationshinweise: ELISA~~1:1,000 Western blotting~~1:100~500 Immunohistochemistry~~1:50~100

Konzentration: 0.25 mg/ml

Reinigung: Purified

Buffer: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Lagerung: Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles

Forschungsgebiet: Apoptose/Nekrose, Krebs, Transkriptionsfaktoren, Signaltransduktion, Zellstruktur

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

Western blot analysis of anti-Bcl2-related Protein A1 Pab (ABIN388092) in human placenta tissue lysate. Bcl2-related Protein A1 (arrow) was detected using purified Pab. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence.

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry. clinical relevance has not been evaluated. BC = breast carcinoma. HC = hepatocarcinoma.

Publikationen

Publikationen: Deng, Gao, May: "Protein phosphatase 2A inactivates Bcl2's antiapoptotic function by dephosphorylation and up-regulation of Bcl2-p53 binding." in: Blood, Vol. 113, Issue 2, pp. 422-8, 2009 (PubMed).