F4/80 Antikörper (Biotin)
Kurzübersicht für F4/80 Antikörper (Biotin) (ABIN380045)
Target
Alle F4/80 (EMR1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Spezifität
- The antigen is a 125kD extracellular membrane protein sensitive to 2-mercaptoethanol. Antigen distribution: Isolated Cells: The antigen is expressed in vitro on over 80 % of M-CSF stimulated bone marrow derived macrophages, after a few days of culture. It is absent from granulocytes, lymphocytes and thrombocytes. Tissue Sections: The antigen is detected on tissue fixed macrophages in all organs tested so far (spleen, lymph nodes, thymus, liver, skin) except lung. It is also present on Langerhans cells in the skin and Kupffer cells in the liver. In complete Freund's adjuvant induced granulomas, the antigen is expressed by inflammatory macrophages, but is absent from epitheloid cells. Specificity: Mouse: major subpopulation of resident tissue macrophages Other species: human heart macrophages
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Aufreinigung
- Affinity purified
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Immunogen
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Cultured macrophages.
Type of Immunogen: Cells -
Isotyp
- IgG2a
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Applikationshinweise
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Approved: IHC, IHC-Fr (1:200)
Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Distilled water
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Konzentration
- Lot specific
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Buffer
- Lyophilized from PBS pH 7.2, 5 mg/mL BSA
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Handhabung
- Avoid freeze-thaw cycles.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Prior to reconstitution, 4°C. Following reconstitution store at -20°C. Avoid freeze-thaw cycles.
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- F4/80 (EMR1) (Egf-Like Module Containing, Mucin-Like, Hormone Receptor-Like 1 (EMR1))
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Andere Bezeichnung
- ADGRE1 / EMR1
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Hintergrund
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Name/Gene ID: ADGRE1
Subfamily: Orphan-B
Family: GPCR
Synonyms: ADGRE1, EMR1 hormone receptor, F4/80, EGF-like module receptor 1, TM7LN3, EMR1 -
Gen-ID
- 2015
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UniProt
- Q14246
Target
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