CD13 Antikörper

Produktnummer ABIN380044

Dieser Ratte Monoklonal Antikörper detektiert spezifisch CD13 in IHC und IHC (p). Es zeigt Reaktivität gegenüber Proben von Maus.

Kurzübersicht für CD13 Antikörper (ABIN380044)

Target: CD13 (ANPEP) (Alanyl (Membrane) Aminopeptidase (ANPEP))

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser CD13 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: ER-BMDM1

Produktdetails anti-CD13 Antikörper

Spezifität: The antigen is a 160  kDa membrane associated protein which shows aminopeptidase N activity. It is homologous to the human CD13 marker. Antigen distribution: Isolated Cells: The antigen is present on the majority of isolated dendritic cells of the spleen and lymph node. Over 80 % of thioglycollate elicited peritoneal exudate macrophages also express the ER-BMDM1 related antigen. It is absent from freshly isolated bone marrow cells and blood cells. Tissue Sections: Lymphoid organs: macrophages surrounding small blood vessels, interdigitating cells, subpopulation of macrophages in the T-cell areas, capsular and medullary cord macrophages in lymph nodes. Non-lymphoid organs: subpopulation of macrophages (mainly in connective tissues) and dendrocytes, structures positive for aminopeptidase such as the brush border of the small intestine, bile canaliculi in the liver and tubuli and glomeruli in the kidney or type II pneumocytes in the lung. Kupffer cells are negative. Specificity: Mouse: Mature macrophages. Other species: not tested.

Aufreinigung: Affinity purified

Immunogen: Cultured monocytes, day 7

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Approved: IHC, IHC-P (1:200)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: 0.5 mL distilled water

Konzentration: Lot specific

Buffer: Lyophilized from PBS  pH 7.2, 10 mg/mL BSA, 0.01 % thimerosal

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 4°C.

Details zu CD13

Target: CD13 (ANPEP) (Alanyl (Membrane) Aminopeptidase (ANPEP))

Andere Bezeichnung: ANPEP / CD13

Hintergrund: Name/Gene ID: ANPEP
Subfamily: Metallopeptidase M1
Family: Exopeptidase

Synonyms: ANPEP, Alanyl aminopeptidase, Aminopeptidase M, APN, Aminopeptidase N, AP-N, AP-M, CD13, CD13 antigen, HAPN, gp150, p150, PEPN, Microsomal aminopeptidase, LAP1

Gen-ID: 290

UniProt: P15144

Pathways: Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones