CD45 Antikörper (PE-Cy5.5)

Produktnummer ABIN376618

Dieser Maus Monoklonal Antikörper detektiert spezifisch CD45 in FACS. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für CD45 Antikörper (PE-Cy5.5) (ABIN376618)

Target: CD45 (PTPRC) (Protein tyrosine Phosphatase, Receptor Type, C (PTPRC))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD45 Antikörper ist konjugiert mit PE-Cy5.5

Applikation: Flow Cytometry (FACS)

Klon: F10-89-4

Produktdetails anti-CD45 Antikörper (PE-Cy5.5)

Spezifität: Human/Horse CD45, Mr 180-220 kDa

Produktmerkmale: Mouse Anti-Human CD45-PE/CY5.5

Aufreinigung: Purified

Immunogen: Purified T cells from human lymph nodes

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise:

• Applications: FC - Quality tested , IHC-FS - Reported in literature , ICC - Reported in literature , IP - Reported in literature , WB - Reported in literature
• Working Dilutions: Flow Cytometry Purified (UNLB) antibody 1 g/106 cells FITC, BIOT, PE, PE/TXRD, APC, SPRD, CY5, PE/CY5.5, 10 L/106 cells PE/CY7, and AF700 conjugates For flow cytometry, the suggested use of these reagents is in a final volume of 100 L

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 100 tests in 1.0 mL of PBS/Sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Protect conjugated products from light.
Each reagent is stable for the period shown on the bottle label if stored as directed.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C

Details zu CD45

Target: CD45 (PTPRC) (Protein tyrosine Phosphatase, Receptor Type, C (PTPRC))

Andere Bezeichnung: CD45

Hintergrund: CD45, also known as the leukocyte common antigen (LCA), exists as four different isoforms (180, 190, 205, 220 kDa) that are generated by alternative splicing of three exons. LCA is found on all cells of hematopoietic origin, except erythrocytes and platelets. CD45 expression is required for T cell and B cell antigen receptor-mediated activation.

Pathways: T-Zell Rezeptor Signalweg, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, CXCR4-mediated Signaling Events, BCR Signaling