CNTF Receptor alpha Antikörper (Internal Region)

Produktnummer ABIN375185

Der Ziege Polyklonal anti-CNTF Receptor alpha Antikörper wird verwendet zum Nachweis von CNTF Receptor alpha in Proben von Maus. Er wurde validiert für WB und EIA.

Kurzübersicht für CNTF Receptor alpha Antikörper (Internal Region) (ABIN375185)

Target: CNTF Receptor alpha (CNTFR) (Ciliary Neurotrophic Factor Receptor (CNTFR))

Reaktivität: Maus

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser CNTF Receptor alpha Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-CNTF Receptor alpha Antikörper

Bindungsspezifität: Internal Region

Spezifität: This antibody reacts to CNTFR.

Kreuzreaktivität (Details): Species reactivity (expected):Human, Rat, Canine.
Species reactivity (tested):Mouse.

Aufreinigung: Affinity chromatography

Immunogen: Peptide with sequence CRSNTYPKGFY, from the internal region of the protein sequence

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: 1/16000. Western Blot: 0.3 - 1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0,5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu CNTF Receptor alpha

Target: CNTF Receptor alpha (CNTFR) (Ciliary Neurotrophic Factor Receptor (CNTFR))

Andere Bezeichnung: CNTFR

Hintergrund: CNTF Receptor alpha is a receptor belonging to the cytokine superfamily of receptors. Along with LIFR and gp130, CNTF Receptor alpha forms the heterotrimeric CNTF receptor complex. The receptor is attached to the membrane by a glycosyl-phosphatidylinositol linkage and contains an immunoglobulin-like C2-type domain and a fibronectin type-III domain. During signal transduction, CNTF first binds to CNTF Recepror alpha, and this permits the recruitment of gp130 and LIFR beta to form the tripartite receptor complex. Signal transduction stimulates gene expression, cell survival or differentiation in a variety of neuronal cell types. Alternative splicing has been observed at this locus and two variants, both encoding the same protein, have been identified.Synonyms: CNTFR, CNTFR alpha, Ciliary neurotrophic factor receptor alpha

Gen-ID: 12804

NCBI Accession: NP_001129528

UniProt: O88507

Pathways: JAK-STAT Signalweg, Feeding Behaviour