MTHFD1 Antikörper (Internal Region)

Produktnummer ABIN375047

Der Ziege Polyklonal anti-MTHFD1 Antikörper wird verwendet zum Nachweis von MTHFD1 in Proben von Human, Maus und Ratte. Er wurde validiert für WB.

Kurzübersicht für MTHFD1 Antikörper (Internal Region) (ABIN375047)

Target: MTHFD1 (Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 1, Methenyltetrahydrofolate Cyclohydrolase, Formyltetrahydrofolate Synthetase (MTHFD1))

Reaktivität: Human, Maus, Ratte

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser MTHFD1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-MTHFD1 Antikörper

Bindungsspezifität: Internal Region

Spezifität: This antibody reacts to MTHFD1.

Kreuzreaktivität (Details): Species reactivity (expected):Mouse, Rat.
Species reactivity (tested):Human.

Aufreinigung: Affinity chromatography

Immunogen: Peptide with sequence RGDLNDCFIPCTPK, from the internal region of the protein sequence

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: 1/1000. Western Blot: 1 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0,5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu MTHFD1

Target: MTHFD1 (Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 1, Methenyltetrahydrofolate Cyclohydrolase, Formyltetrahydrofolate Synthetase (MTHFD1))

Andere Bezeichnung: MTHFD1

Hintergrund: MTHFD1 is a protein that possesses three distinct enzymatic activities, 5,10-methylenetetrahydrofolate dehydrogenase, 5,10-methenyltetrahydrofolate cyclohydrolase and 10-formyltetrahydrofolate synthetase. Each of these activities catalyzes one of three sequential reactions in the interconversion of 1-carbon derivatives of tetrahydrofolate, which are substrates for methionine, thymidylate, and de novo purine syntheses. The trifunctional enzymatic activities are conferred by two major domains, an aminoterminal portion containing the dehydrogenase and cyclohydrolase activities and a larger synthetase domain. In the N terminal section it belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family. In the C terminal section it belongs to the formate tetrahydrofolate ligase family.Synonyms: C-1-tetrahydrofolate synthase, C1-THF synthase, MTHFC, MTHFD, cytoplasmic

Gen-ID: 4522, 9606

UniProt: P11586

Pathways: Methionine Biosynthetic Process