Kallikrein 5 Antikörper (Internal Region)

Produktnummer ABIN374828

Der Ziege Polyklonal anti-Kallikrein 5 Antikörper wird verwendet zum Nachweis von Kallikrein 5 in Proben von Human, Ratte und Hund. Er wurde validiert für WB.

Kurzübersicht für Kallikrein 5 Antikörper (Internal Region) (ABIN374828)

Target: Kallikrein 5 (KLK5)

Reaktivität: Human, Ratte, Hund

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser Kallikrein 5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Kallikrein 5 Antikörper

Bindungsspezifität: Internal Region

Spezifität: This antibody recognizes KLK5.

Kreuzreaktivität (Details): Species reactivity (expected):Rat and Canine.
Species reactivity (tested):Human.

Aufreinigung: Affinity Chromatography.

Immunogen: Peptide with sequence KAGRDSCQGD, from the internal region of the protein sequence

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: 1/4000. Western Blot: 0.1-0.3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu Kallikrein 5

Target: Kallikrein 5 (KLK5)

Andere Bezeichnung: KLK5 / Kallikrein-5

Hintergrund: Kallikrein 5 was originally described from the skin as an enzyme involved in turnover of the stratum corneum, and later cloned from human EST libraries as a Kallikrein like enzyme. The skin is known to contain trypsin like and chymotrypsin like proteinases of 32 kDa and 25 kDa respectively, and these were determined to be hK5 and hK7. Kallikrein 5 is found is greatest abundance in the skin, and also in the brain, with lesser signal in the kidney, lung, mammary gland, and testis. Human breast milk is reported to contain high levels of Kallikrein 5. Less stringent PCR detects hK5 in many tissues, and analysis of cell lines by Western blot shows that many cell lines make hK5.Synonyms: KLK-5, KLK-L2, Kallikrein-Like Protein 2, SCTE, Stratum corneum tryptic enzyme

Gen-ID: 25818

NCBI Accession: NP_001070959

UniProt: Q9Y337

Pathways: Komplementsystem, Regulation of G-Protein Coupled Receptor Protein Signaling