ARPC1B Antikörper (N-Term)

Produktnummer ABIN374216

Der Ziege Polyklonal anti-ARPC1B Antikörper wird verwendet zum Nachweis von ARPC1B in Proben von Human, Maus, Ratte, Rind (Kuh), Hund und Schwein. Er wurde validiert für WB.

Kurzübersicht für ARPC1B Antikörper (N-Term) (ABIN374216)

Target: ARPC1B (Actin Related Protein 2/3 Complex, Subunit 1B, 41kDa (ARPC1B))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Schwein

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser ARPC1B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ARPC1B Antikörper

Bindungsspezifität: N-Term

Sequenz: AYHSFLVEPI SCH

Spezifität: This antibody detects ARPC1B / ARC41 at N-term.

Kreuzreaktivität (Details): Species reactivity (expected):Mouse, Rat, Dog, Pig, Cow.
Species reactivity (tested):Human.

Aufreinigung: Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

Immunogen: Peptide from N Terminus of the protein sequence according to NP_005711.1 Genename: ARPC1B

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: Limit dilution 1: 32000. Western blot: 2-4 μg/mL. Approx 37 kDa band observed in Human Liver lysates (calculatedMW of 40.7 kDa according to NP_005711). A minor band of unknown identity was alsoconsistently observed at 27 kDa.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C.

Details zu ARPC1B

Target: ARPC1B (Actin Related Protein 2/3 Complex, Subunit 1B, 41kDa (ARPC1B))

Andere Bezeichnung: ARPC1B / ARC41

Hintergrund: ARP2/3 subunit 1B (ARPC1B) is one of seven subunits of the human Arp2/3 protein complex. It is a member of the SOP2 family of proteins and is most similar to the protein encoded by gene ARPC1A. The similarity between these two proteins suggests that they both may function as p41 subunit of the human Arp2/3 complex that has been implicated in the control of actin polymerization in cells. It is possible that the p41 subunit is involved in assembling and maintaining the structure of the Arp2/3 complex. Multiple versions of the p41 subunit may adapt the functions of the complex to different cell types or developmental stages.Synonyms: Actin-related protein 2/3 complex subunit 1B, Arp2/3 complex 41 kDa subunit, p41-ARC

Gen-ID: 10095

NCBI Accession: NP_005711

UniProt: O15143

Pathways: RTK Signalweg, Regulation of Actin Filament Polymerization