MARK4 Antikörper (C-Term)

Produktnummer ABIN374191

Dieser Ziege Polyklonal Antikörper detektiert spezifisch MARK4 in WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für MARK4 Antikörper (C-Term) (ABIN374191)

Target: MARK4 (MAP/microtubule Affinity-Regulating Kinase 4 (MARK4))

Reaktivität: Human

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser MARK4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-MARK4 Antikörper

Bindungsspezifität: C-Term

Sequenz: IKRKPPPGCS DSPGV

Spezifität: This antibody detects MARK4 at C-term.

Aufreinigung: Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

Immunogen: Peptide from the C Terminus of the protein sequence according to NP_113605.2. Genename: MARK4

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: Limit dilution 1: 128000. Western blot: 0.3-1 μg/mL. Approx 70 kDa band observed in human prostate lysates(calculated MW of 75.0 kDa according to NP_113605.2).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C.

Details zu MARK4

Target: MARK4 (MAP/microtubule Affinity-Regulating Kinase 4 (MARK4))

Andere Bezeichnung: MARK4

Hintergrund: MARK4 contains an N terminal serine/threonine kinase domain, a central ubiquitin associated domain, and a C terminal KA1 associated kinase domain. RT PCR analysis detects upregulated expression of the gene for MARK4 in nearly all clinical hepatocellular carcinoma cells. Northern blot analysis reveals ubiquitous expression of a 3.6kb transcript, with highest expression in testis. Immunofluorescence microscopy demonstrates homogeneous cytoplasmic expression. Colony forming assays show that MARK4 antisense reduces the growth of SNU475 cells. It has been suggested that MARK4 provides a growth advantage to cells.Synonyms: MAP microtubule affinity-regulating kinase 4, MARKL1

Gen-ID: 57787

NCBI Accession: NP_113605

UniProt: Q96L34