GADD34 Antikörper (C-Term)
Kurzübersicht für GADD34 Antikörper (C-Term) (ABIN374070)
Target
Alle GADD34 (PPP1R15A) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Sequenz
- C-AAALDLSGRR G
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Spezifität
- This antibody detects GADD34 / PPP1R15A at C-term.
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Kreuzreaktivität (Details)
- Species reactivity (tested):Human, Mouse.
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Aufreinigung
- Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide
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Immunogen
- Peptide from the C Terminus of the protein according to NP_055145.3. Genename: PPP1R15A
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Applikationshinweise
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ELISA: 1: 128000. Western blot: 0.1-0.3 μg/mL. Approx 75 kDa band observed in lysates of cell line HEPG2(calculated MW of 73.5 kDa according to NP_055145.2).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 0.5 mg/mL
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Buffer
- Tris saline, 0.02 % Sodium Azide, pH 7.3 with 0.5 % BSA
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- GADD34 (PPP1R15A) (Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 15A (PPP1R15A))
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Andere Bezeichnung
- GADD34 / PPP1R15A
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Hintergrund
- A protein phosphatase whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents.Synonyms: Growth arrest and DNA damage-inducible protein GADD34, Myeloid differentiation primary response protein MyD116 homolog, Protein phosphatase 1 regulatory subunit 15A
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Gen-ID
- 23645
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NCBI Accession
- NP_055145
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UniProt
- O75807
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Pathways
- ER-Nucleus Signaling, Unfolded Protein Response
Target
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